Prolotherapy is an older treatment in which a sugar solution is injected into joints. Do not rely on medicine for pain relief. Always try non-drug options, such as exercise, weight loss, physical therapy, and hot and cold packs.
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Show references Rosenquist EWK. Overview of the treatment of chronic non-cancer pain. Accessed May 30, Factors that affect arthritis pain. Arthritis Foundation. Natural relief for arthritis pain. Managing chronic pain: How psychologists help with pain management. American Psychological Association.
Benefits of exercise for osteoarthritis. Topical agents are typically used to provide symptomatic relief and are not routinely used for the long-term management of OA or inflammatory arthritis.
Sometimes over-the-counter medications are not strong enough to treat the pain caused by arthritis. In this case, your health-care provider may recommend other prescription pain medications, such as tramadol , an opioid or duloxetine. Tramadol, opioids and duloxetine may be used to treat osteoarthritis OA pain. Tramadol and opioids may also sometimes be used to treat short-term inflammatory arthritis.
Opioids are second-line medications reserved for moderate to severe knee and hip OA pain that does not respond to other therapies acetaminophen, NSAIDs or tramadol. Opioids are not routinely used to treat OA pain as adverse effects limit their use in many patients. Duloxetine is a second-line agent that may be used to treat OA of the knee.
Duloxetine has also shown benefit as an add-on medication for people who have had a partial response to acetaminophen or NSAIDs. Opioids and tramadol may also be used for short periods of time to help treat pain associated with inflammatory arthritis.
Tramadol and duloxetine are taken orally in pill form. Opioids are typically taken orally. For people living with OA, your health-care provider may recommend tramadol or duloxetine depending on your level of pain and response to acetaminophen and NSAIDs.
Opioids are not routinely used to treat OA pain, but may be considered if pain relief is not achieved from other medications. The beneficial effects of opioids on OA are often outweighed by their increased risks of adverse events. Opioids are generally recommended for short-term use in the management of OA.
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